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Watch five-time Oscar-nominated film 'The Substance' on Amazon Prime Video this weekend


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Is there an Academy Award for best comeback? Because I think that honor would belong to Demi Moore. The 62-year-old actress has been appearing in Hollywood blockbusters since the 1980's and is eyeing an Oscar at the 96th Annual Academy Awards for her role as the actress in 'The Substance.'

The 2025 Academy Awards will take place on Sunday, March 2. A total of 24 award categories will be presented, including the highly coveted 'Big Five.' Among those top awards are Best Motion Picture, Best Director, Best Screenplay, Best Leading Actor and Best Leading Actress.

Demi Moore is among those nominated for Best Leading Actress for her role in the science-fiction, horror film, 'The Substance.' Here's what you need to know about 'The Substance' prior to the awards ceremony:

How to watch Oscar-nominated film 'The Substance'

'The Substance' is a sci-fi, horror film where actress Elisabeth Sparkle loses her job in an aerobics show as a sign of her career starting to fade. She decides to inject herself with a mysterious serum that is meant to improve her looks, making her look younger, but things began to go awry.

This horror film stars Demi Moore as Elisabeth Sparkle, Margaret Qualley as Sue and Dennis Quaid as Harvey. The movie debuted in September 2024, and has grossed over $82 million worldwide, according to Box Office Mojo.

'The Substance' is available to rent on Amazon Prime Video today.

Watch The Substance on Prime Video

What awards is 'The Substance' nominated for at the 2025 Oscars? 

'The Substance' is nominated in five categories for the 2025 Academy Awards. Here's a look at the Oscars the film could potentially bring home:

  • Best Achievement in Makeup and Hairstyling
  • Best Motion Picture
  • Best Achievement in Directing
  • Best Performance by an Actress in a Leading Role
  • Best Original Screenplay

What awards has 'The Substance' won so far? 

It's not often that a horror film wins Best Motion Picture at the Academy Awards. In fact, the last time was in 1992 for 'Silence of the Lambs.' So, The Substance is hoping to join a very short list.

'The Substance' was nominated for five total British Academy of Film and Television Arts awards, but it only won in one category: Best Make Up & Hair.

It was nominated for seven total Critics' Choice Award, winning in three categories: Best Hair & Makeup, Best Actress and Best Original Screenplay.

'The Substance' was also nominated for five Golden Globes, where it won Best Performance by a Female Actor in a Motion Picture, Musical or Comedy. It was only nominated for one Screen Actors Guild Award, and it won in that one category: Outstanding Performance by a Female Actor in a Leading Role.

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