Houston vs Gonzaga prediction, picks for 2025 men's NCAA Tournament
It's Houston vs Gonzaga in the 2025 NCAA Tournament second round. See our expert picks and predictions for the March Madness bracket, along with how to watch and game time.

The 2025 NCAA Tournament is in full swing. The first round is in the books, cutting the field from 64 to 32.
Second-round action on Saturday features a matchup between Houston and Gonzaga in the Midwest Region.
The Houston Cougars earned a No. 1 seed in the 2025 March Madness bracket and won the battle of the cougars, knocking off the SIU Edwardsville Cougars in the first round. Houston's opponent, the 8-seeded Gonzaga Bulldogs dominated the battle of the bulldogs, emerging victorious over the Georgia Bulldogs on Thursday.
Houston ranks as the third-best team in the KenPom rankings, sporting the 11th-best offense and second-best defense. Meanwhile, Gonzaga ranks seventh overall with the seventh-ranked offense and 26th-ranked defense.
Here's how our experts see Saturday's Round of 32 clash playing out. Be sure to check out Paste BN's complete March Madness bracket predictions to see our team's picks for every game. While you're at it, don't forget to read our tournament bold predictions and upset picks.
Houston vs. Gonzaga picks and predictions
- Jordan Mendoza: Houston
- Zac Al-Khateeb: Gonzaga
- Kevin Skiver: Gonzaga
- Chris Thomas: Houston
- Paul Myerberg: Houston
- Erick Smith: Houston
- Eddie Timanus: Houston
- Dan Wolken: Houston
- Jeremy Cluff: Houston 75, Gonzaga 65
- Sportsbook Wire: Houston 74, Gonzaga 71
Our experts are backing Houston to get the win in this contest. AZ Central's Jeremy Cluff is taking Houston to cover the 5.5-point spread, while Paste BN's Sportsbook Wire is taking the points with Gonzaga. Both of them are taking the over 139.5-point total.
Houston vs. Gonzaga date, start time, where to watch
- Game Day: Saturday, March 22, 2025
- Game Time: 8:40 p.m. ET
- Location: INTRUST Bank Arena in Wichita, Kansas
- TV Channel: TNT
- Live Stream: Sling TV - Watch Now!
Watch Houston vs. Gonzaga on Sling TV
Houston vs. Gonzaga odds
Odds as of Friday, March 21 via BetMGM.
- Spread: Houston -5.5 (-105)
- Moneyline Favorite: Houston -225
- Moneyline Underdog: Gonzaga +185
- Total: 139.5
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