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UCLA vs. Southern predictions, picks for 2025 women's NCAA Tournament


It's UCLA vs. Southern in the 2025 women's NCAA Tournament first round. See our expert picks and predictions for the women's March Madness bracket, along with betting odds and game time.

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Editor's note: Follow Women's March Madness live updates and scores from Friday's first-round action.

The 2025 NCAA women's tournament is here. Wrapping up the first-round action Friday night will be UCLA and Southern.

The UCLA Bruins finished the 2024-25 season with a 30-2 record and punctuated it with a Big Ten tournament championship. That earned them the No. 1 seed in the 2025 women's March Madness bracket. Their opponent, the No. 16-seeded Southern Jaguars, defeated UC San Diego in the First Four after claiming the Southwestern Athletic title.

UCLA is ranked fourth in the country in efficiency by Barttorvik, while Southern is ranked 67th in defensive efficiency.

Here's how our experts see Friday's clash playing out. Be sure to check Paste BN's complete March Madness bracket breakdown for in-depth analysis. Don't forget to read tournament upset picks and players who could make a splash.

Here are our UCLA vs. Southern picks and predictions.

UCLA vs. Southern picks, predictions

Our experts from across the Paste BN Network are unanimous (8-0) on who will win this game,  No. 1 seed Bruins or No. 16 seed Jaguars. UCLA does have the edge in efficiency statistics. Take a look at their full bracket predictions.

UCLA vs. Southern date, start time, how to watch

  • Game Day: March 21
  • Game Time: 10 p.m. ET
  • Location: Pauley Pavilion in Los Angeles
  • TV Channel: ESPN
  • Live Stream: Fubo - Watch Now!

Watch UCLA vs. Southern on Fubo

UCLA vs. Southern odds

Odds via DraftKings as of Thursday, March 20.

  • Spread: UCLA -41.5
  • Moneyline Favorite: OTB
  • Moneyline Underdog: OTB
  • Total: 121.5

Women's March Madness game-by-game predictions for Friday

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