Southern Cal vs Mississippi State prediction, picks for 2025 women's NCAA Tournament
It's USC vs. Mississippi State in the 2025 NCAA Tournament second round. See our expert picks and predictions for the women's March Madness bracket, along with betting odds and game time.
The 2025 NCAA women's tournament is in full force, folks.
Among the Monday second-round matchups will be a bout between Southern Cal and Mississippi State.
The USC Trojans defeated UNC Greensboro in the first round following a regular season that earned them a 1 seed in the 2025 women's March Madness bracket. Their opponent, the 9-seeded Mississippi State Bulldogs, took down Cal in their first-round matchup.
Here's how our experts see the Round of 32 clash playing out. Be sure to check out Paste BN's complete March Madness bracket breakdown for in-depth analysis. While you're at it, don't forget to read our tournament upset picks and players who could make a splash.
Without further ado, here are our USC vs. Mississippi State picks and predictions.
USC vs. Mississippi State picks and predictions
Our experts from across the Paste BN Network are split 3-3 on who will win the second-round game, LSU or Florida State. Take a look at their full bracket predictions.
Sam Sklar, Clarion Ledger: USC 75, Mississippi State 64
In the Clarion Ledger, Sklar writes: "The Bulldogs can win this game, but a lot will need to go right. It starts with taking care of the basketball while trying to replicate Saturday's defensive effort. However, it's hard to see MSU keeping up with USC's offense, especially in front of what should be a raucous home crowd."
Nancy Armour, Paste BN: USC
Jordan Mendoza, Paste BN: USC
Cydney Henderson, Paste BN: USC
Meg L. Hall, For The Win: USC
Cora Hall, Knoxville News: USC
USC vs. Mississippi State date, start time, how to watch
- Game Day: Monday, March 24, 2025
- Game Time: 10 p.m. ET
- Location: Galen Center in Los Angeles
- TV Channel: ESPN
- Live Stream: Fubo - Watch Now!
Watch USC vs. Mississippi State on Fubo (free trial)
USC vs. Mississippi State odds
Odds via BetMGM as of Sunday, March 23.
- Spread: USC -17.5
- Moneyline Favorite: USC -3000
- Moneyline Underdog: Mississippi State +1200
- Total: 147.5
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