San Francisco 49ers at Minnesota Vikings: Predictions, picks and odds for NFL Week 7 game

Show Caption

"Monday Night Football" for Week 7 will take place in U.S. Bank Stadium as the Minnesota Vikings (2-4) will host the San Francisco 49ers (5-1).

It was a magnificent start to the season for San Francisco, but the run toward perfection ended in a close loss to the Cleveland Browns. There were all sorts of miscues that doomed the 49ers, but injuries to weapons like Deebo Samuel and Christian McCaffrey could cause concern for what has been a flourishing offense.

Without star receiver Justin Jefferson, the Vikings were able to avoid the bottom of the NFC North by putting the clamps on the Chicago Bears in a 19-13 road win. There has been lots of talk surrounding a Kirk Cousins trade, but those could be put to rest with a big win against a Super Bowl contender.

PROP TALK: These are the best prop bets for NFL games this week

Vikings vs. 49ers odds, moneyline, over/under

The 49ers are favorites to defeat the Vikings, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023.

Spread: 49ers (-6.5)
Moneyline: 49ers (-300); Vikings (+240)
Over/under: 44

Not interested in this game? Our guide to the NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.

If you’re new to sports betting, don’t worry. We have tips for beginners on how to place bet online. And Paste BN readers can claim exclusive promos and bonus codes with the online sportsbooks and sports betting sites.

MOST VALUABLE BET: These are the best NFL MVP betting odds

NFL Week 7 odds, predictions and picks

Lorenzo Reyes: 49ers 33, Vikings 20

Definitely wait for closer to game time to watch the updates on the injuries of 49ers stars Deebo Samuel, Christian McCaffrey and Trent Williams, but I think this is an excellent position for San Francisco to bounce back. The Vikings, meanwhile, were unspectacular against a weak Bears squad.

Tyler Dragon: 49ers 28, Vikings 13

Expect the 49ers to bounce back after a surprising loss to the Browns in Week 6. Christian McCaffrey, Deebo Samuel and Trent Williams are all battling injuries. But the 49ers still have enough talent to beat a struggling Vikings team sans Justin Jefferson. Minnesota has a league-worst 13 giveaways.

Safid Deen: 49ers 27, Vikings 17

This would’ve been a better Monday night matchup if injuries weren’t a factor. It appears running back Christian McCaffrey (oblique/rib), Deebo Samuel (shoulder), and left tackle Trent Williams (right ankle) could all miss this game, which would be better for San Francisco’s potential Super Bowl run. The Vikings weren’t doing well before star receiver Justin Jefferson’s hamstring injury, and won’t do any better against a 49ers team that’s significantly loaded with depth behind their injured stars.

Victoria Hernandez: 49ers 24, Vikings 19

Christian McCaffery’s touchdown streak could be over as he hurt his oblique last week and is a question mark for this game along with Deebo Samuel and Trent Williams. For the Vikings, TJ Hockenson has stepped up in Justin Jefferson’s absence, as he should with the money he’s making. Ultimately, Brock Purdy has more tools at his disposal and a stout defense to rely on.

Jordan Mendoza: 49ers 22, Vikings 13

All eyes will be on whether Christian McCaffrey and Deebo Samuel can suit up for San Francisco as the offense struggled without its key pieces in the first loss of the season. But even if they don't play, the 49ers defense will create fits for a Minnesota offense that's still not anything impressive.

You can view the full list of Paste BN's NFL expert predictions here.

PROP TALK: These are the best prop bets for NFL games this week

NFL salaries: These are the highest paid NFL players

Gannett may earn revenue from sports betting operators for audience referrals to betting services. Sports betting operators have no influence over nor are any such revenues in any way dependent on or linked to the newsrooms or news coverage. Terms apply, see operator site for Terms and Conditions. If you or someone you know has a gambling problem, help is available. Call the National Council on Problem Gambling 24/7 at 1-800-GAMBLER (NJ, OH), 1-800-522-4700 (CO), 1-800-BETS-OFF (IA), 1-800-9-WITH-IT (IN). Must be 21 or older to gamble. Sports betting and gambling are not legal in all locations. Be sure to comply with laws applicable where you reside.

Facebook Twitter Email