New York Giants at Dallas Cowboys: Predictions, picks and odds for NFL Week 10 game

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The Dallas Cowboys (5-3) host the New York Giants (2-7) in an NFC East clash in Week 9.

The Cowboys are coming off a bruising 28-23 division loss to the Philadelphia Eagles. Dak Prescott threw three touchdowns to three different receivers, but was sacked five times. Dallas had the ball on the last drive with a chance to win, but fumbled the game away.

The Giants will be under the leadership of Tommy DeVito for the rest of the season as Daniel Jones tore his ACL in the 30-6 loss to the Las Vegas Raiders. Tyrod Taylor is on injured reserve with a rib injury he suffered a week earlier. DeVito went 15-of-20 for 175 yards, a touchdown and two interceptions in last week's effort.

The Cowboys smacked the Giants 40-0 to open the season. Dallas has since lost All-Pro cornerback Trevon Diggs to a torn ACL.

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Cowboys vs. Giants odds, moneyline, over/under

The Cowboys are favorites to defeat the Giants, according to the BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023, including the new ESPN BET app.

Spread: Cowboys (-17)
Moneyline: Cowboys (-2000); Giants (+1000)
Over/under: 39

Not interested in this game? Our guide to the NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.

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NFL Week 10 odds, predictions and picks

Lorenzo Reyes: Cowboys 31, Giants 0

I just don’t see any way the Giants win or cover here. Only way is if Dallas sleepwalks through it. New York is dealing with injuries, has no offensive identity and Dallas’ defense should feast on Tommy DeVito. I love the under here, too, which has hit in eight of New York’s nine games this season, including the last seven.

Tyler Dragon: Cowboys 30, Giants 16

The Giants' nightmare season continues. Daniel Jones (knee) is lost for the season and Tyrod Taylor (rib cage), who’s outplayed Jones this year, is on injured reserve. The Cowboys lost to Philadelphia last week, but their performance proved they are contenders in the NFC.

Safid Deen: Cowboys 34, Giants 10

It felt like the Cowboys were inches away from upsetting the Eagles last week, and that feeling of coming so close will fuel them to blowout the Giants this week. The Giants have nothing offensively and will be picking a quarterback in the draft next year.

Victoria Hernandez: Cowboys 32, Giants 10

The Cowboys impressed with their Week 1 thrashing of the Giants and have cooled off since then. But New York is playing with rookie Tommy DeVito under center and can’t put all their weight on Saquon Barkley. Dallas will win at home and there’s no reason they won’t cover that massive spread.

Jordan Mendoza: Cowboys 38, Giants 6

The first matchup this season was a complete blowout. With the injuries piling up in New York, expect much of the same this time around and the spread to be covered. Consider any points the Giants score a success.

You can view the full list of Paste BN's NFL expert predictions here.

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