Carolina Panthers at Tennessee Titans: Predictions, picks and odds for NFL Week 12 game

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Both the Tennessee Titans (3-7) and Carolina Panthers (1-9) need to snap a three-game losing streak with their Week 12 matchup at Nissan Stadium between the 29th and 32nd worst offenses in the NFL.

Derrick Henry has just two games of 100+ yards this season and notched 38 yards in last week's 34-14 loss to the Jacksonville Jaguars. Ryan Tannehill will be back on the Titans' active roster, but rookie Will Levis will remain the starter.

The Panthers lost 33-10 to the Dallas Cowboys last week and have scored a total of 36 points in their last three games, all losses. Rookie quarterback Bryce Young had a season low 123 passing yards against the staunch Dallas defense.

Will the Titans be able to find power behind their veteran running back? Or will the Panthers be the ones to rebound?

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Titans vs. Panthers odds, moneyline, over/under

The Titans are favorites to defeat the Panthers, according to BetMGM NFL odds. Looking to wager? Check out the best mobile sports betting apps offering NFL betting promos in 2023, including the new ESPN BET app.

Spread: Titans (-3.5)
Moneyline: Titans (-185); Panthers (+150)
Over/under: 36.5

Not interested in this game? Our guide to NFL betting odds, picks and spreads has you covered with Thursday Night Football odds, Sunday Night Football odds and/or Monday Night Football odds.

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NFL Week 12 odds, predictions and picks

Lorenzo Reyes: Titans 15, Panthers 14

Frankly, I’d stay away from this one. Neither team is reliable, and while Tennessee has a 4-5 record against the spread, it is just 1-5 over its last six games. I could see Carolina winning this one outright. But, again, I’m not confident one way or the other.

Tyler Dragon: Titans 21, Panthers 20

It’s too premature to judge Bryce Young. The Panthers have a leaky offensive line and don’t have much talent around him. Frank Reich might not even be the right coach in Carolina. Titans rookie QB Will Levis has made some flashes but rookie growing pains have affected his performance. Derrick Henry and Tennessee’s ability to win the battle in the trenches will be enough for the Titans to be triumphant.

Safid Deen: Titans 27, Panthers 14

The Titans haven’t been in many games this season, but this matchup could favor them. They’re rugged and beaten up enough to take care of business against the Panthers at home.

Victoria Hernandez: Titans 17, Panthers 12

The Titans are finally home after a three-game road stretch where they dropped all three matchups. The Panthers have averaged a lowly 12 points per game in their last three games, all losses, and there's no evidence that their offense will suddenly kickstart here.

Jordan Mendoza: Panthers 16, Titans 14

Carolina is slowly making progress in Bryce Young’s rookie season, while Tennessee is unraveling with Will Levis at quarterback. This seems like a game Tennessee could overlook, meaning Carolina gets its first road win of the season.

You can view the full list of Paste BN's NFL expert predictions here.

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