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Carolina Panthers at New Orleans Saints odds, picks and predictions


The Carolina Panthers (6-10) finish their season against the New Orleans Saints (7-9) in the Caesars Superdome Sunday at 1 p.m. ET (FOX). Below, we analyze Tipico Sportsbook's lines around the Panthers vs. Saintsodds, and make our expert NFL picks and predictions.

The 2022 season was not kind to the Panthers and Saints. Both came in with postseason aspirations - or at the very least finishing better than .500 - but they find themselves out of the playoff picture when they take the field Sunday.

The NFC South rivals faced off in Week 3 with the Panthers, as 9.5-point home underdogs, upsetting the Saints 22-14. QB Baker Mayfield (now with the Rams) and RB Christian McCaffrey (now with 49ers) started for Carolina, while QB Jameis Winston (season-ending injury) and WR Michael Thomas (on injured reserve) started for New Orleans. They won't be involved Sunday, so little can be taken from that 1st game to analyze this one.

Both teams are eliminated and will end with losing records. The Panthers controlled their destiny entering Week 17 but lost as 3.5-point road underdogs to Tampa Bay 30-24. The Saints surprisingly upset a Jalen Hurt-less Eagles 20-10 last week - New Orleans was a 5.5-point road dog.

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Panthers at Saints odds

Provided by Tipico Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 3:14 a.m. ET.

  • Moneyline (ML) : Panthers +155 (bet $100 to win $155) | Saints -180 (bet $180 to win $100)
  • Against the spread (ATS) : Panthers +3.5 (-115) | Saints -3.5 (-105)
  • Over/Under (O/U) : 41.5 (O: -111 | U: -109)

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Panthers at Saints key injuries

Panthers

  • DL Brian Burns (ankle) questionable
  • RB D'Onta Foreman (knee) questionable
  • DL Yetur Gross-Matos (hamstring) questionable
  • DL Matthew Ioannidis (back) questionable

Saints

  • CB Paulson Adebo (hamstring) out
  • TE Taysom Hill (back) questionable
  • OL James Hurst (foot) questionable
  • TE Juwan Johnson (quad) questionable
  • S Marcus Maye (shoulder) questionable
  • OL Andrus Peat (ankle) questionable
  • OL Ryan Ramczyk (hip) questionable

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Panthers at Saints picks and predictions

Prediction

Saints 17, Panthers 16

Moneyline

Despite their record, the Saints are pretty good against the pass. They are 3rd in passing yards allowed per game (193.9) and 4th in opponent yards per pass (6.0).

The run game is a different story. After the Panthers put up 320 rushing yards against the Lions in Week 16, they could harass a New Orleans team that's 23rd in yards per rush (4.5). The moneyline odds should be AVOIDED but you may consider a rushing prop.

Against the spread

The Saints are 1-5 against the spread in their past 6 games when their defense holds opponents to 90 rushing yards or less in their previous game.

On top of that, the Panthers have covered in 7 of their last 8 games after hitting more than 350 total yards in their last game.

BET PANTHERS +3.5 (-115).

Over/Under

Both teams lean toward the Under. The Panthers hit the Under is 5 of their last 7 games after an ATS loss.