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Louisville at Duke odds, picks and predictions


The Louisville Cardinals (4-23, 2-14 ACC) take on the Duke Blue Devils (19-8, 10-6) on Monday at Cameron Indoor Stadium. Tip-off is set for 7 p.m. ET (ESPN). Below, we analyze Tipico Sportsbook's lines around the Louisville vs. Dukeodds, and make our expert college basketball picks, predictions and bets.

The Cardinals defeated Clemson 83-73 on Saturday as 10.5-point underdogs at home. Louisville ended a 4-game losing streak with its win over Clemson and has lost 8 of its last 10 games.

The Blue Devils beat Syracuse 77-55 on Saturday and covered as 1-point favorites on the road. Duke has won 2 games in a row and 6 of its last 10 contests.

This is the only regular-season meeting between Louisville and Duke this season. The road team has won each of the last 3 meetings.

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Louisville at Duke odds

Provided by Tipico Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 8:16 a.m. ET.

  • Moneyline (ML) : Louisville +875 (bet $100 to win $875) | Duke -2500 (bet $2,500 to win $100)
  • Against the spread (ATS) : Louisville +18.5 (-110) | Duke -18.5 (-110)
  • Over/Under (O/U) : 137.5 (O: -110 | U: -110)

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Louisville at Duke picks and predictions

Prediction

Duke 78, Louisville 63

Moneyline

AVOID.

While Duke should come away with a win at home, taking the Blue Devils straight up at the current odds (-2500) isn't a wise decision.

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Against the spread

BET LOUISVILLE +18.5 (-110).

It's unlikely that the Cardinals go into Cameron Indoor and defeat the Blue Devils, but Louisville is coming off its most impressive win over Clemson and has kept games close recently.

The Cardinals are 5-1 ATS in their last 6 games overall and the Blue Devils are 0-8 ATS in their last 8 games following an ATS win.

Over/Under

With Duke averaging a solid 71.6 points per game (175th in the nation) and Louisville allowing 75.4 points per game (326th in the nation), I lean toward the OVER 137.5 (-110). The Cardinals have also scored 65-plus points in 5 of their last 8 games.

Louisville has gone Over in 4 of its last 5 games overall.

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