Manchester City vs. Arsenal odds, picks and predictions

In a high-profile English Premier League clash, Manchester City (22 wins, 4 losses, 4 draws) welcomes Arsenal (23-3-6) to Etihad Stadium. Kickoff is set for 3 p.m. ET. Below, we preview BetMGM Sportsbook's lines around the Manchester City vs. Arsenal odds, and make our best EPL bets, picks and predictions.

This game could very well decide the fate of the 2022-23 English Premier League season. City is 2 games behind Arsenal and is 5 points behind them for the top spot in the league. Both teams are locked into top-4 spots which will qualify the clubs for the UEFA Champions League next season.

City is an impressive 13-1-1 at home this season. It is led offensively by F Erling Haaland, who has 32 goals in 28 matches. City has won 6 straight EPL matches and hasn't drawn or lost at home in a league match this calendar year.

Arsenal is 11-2-3 on the road this season. The Reds are led by F Martinelli, who has 15 goals on the season. F Bukayo Saka and M Martin Odegaard both have 10-plus goals as well. Arsenal has drawn 3 straight league matches, 2 of which were on the road.