First look: Denver Broncos at Buffalo Bills odds and lines

Skip Snow | Staff Writer

The Denver Broncos (3-5) and Buffalo Bills (5-4) clash in the Week 10 Monday Night Game. The AFC tilt at Highmark Stadium will kick off at 8:15 p.m. ET (ABC). Below, we look at Broncos vs. Bills odds from BetMGM Sportsbook. Also see: SportsbookWire's NFL picks and predictions.

Denver is coming off a bye week. The Broncos last played Oct. 29, upsetting the Kansas City Chiefs 24-9 as a +7 underdog. The win marked Denver's 1st as an underdog since Week 8 of last season.

The Bills were at Cincinnati in the Week 9 Sunday nighter. Buffalo dropped its 5th straight game against the spread, falling 24-18 as a +1.5 underdog. The Bills had 2 costly turnovers and were a -2 in TO margin. They fumbled at the Bengal 22-yard line and threw an interception in their own end.

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Broncos at Bills odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 1:52 p.m. ET.

Moneyline: Broncos +310 (bet $100 to win $310) | Bills -400 (bet $400 to win $100)
Against the spread (ATS): Broncos +7.5 (-110) | Bills -7.5 (-110)
Over/Under (O/U): 46.5 (O: -110 | U: -110)

2023 betting stats

ML: Broncos 3-5 | Bills 5-4
ATS: Broncos 2-5-1 | Bills 3-6
O/U: Broncos 4-4 | Bills 3-6

Broncos vs. Bills head-to-head

The Broncos and Bills 1st met in 1960 and have played 40 times (including 1 postseason game), with Buffalo ahead 23-16-1.

Meetings of recent vintage have gone Buffalo's way. The Bills have won 3 straight games and 5 of the last 6. In Buffalo, the Bills have won 3 in a row.

Against the number, the Bills have gone 7-0 since 2007. The most recent of those meetings in 2020, when a favored-by-6 Buffalo team defeated the Broncos 48-19 in Denver.

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