First look: Tampa Bay Buccaneers at San Francisco 49ers odds and lines

Jess Root | Staff Writer

The Tampa Bay Buccaneers (4-5) will travel to Northern California in Week 11 to face the San Francisco 49ers (6-3) on Sunday. Kickoff at at Levis Stadium in Santa Clara is 4:05 p.m. ET (FOX). Below, we look at Buccaneers vs. 49ers odds from BetMGM Sportsbook. Also see: SportsbookWire's NFL picks and predictions.

The Bucs snapped a 4-game losing streak on Sunday, defeating the Tennessee Titans 20-6 as 2.5-point home favorites, with the Under (39.5) cashing in. They are a half-game behind the New Orleans Saints for the NFC South division lead.

The 49ers, coming off the bye week, snapped a 3-game losing streak with a 34-3 road win over the Jacksonville Jaguars as 3-point favorites. The Under (44.5) hit in the victory. They have the same record as the Seattle Seahawks, but hold a divisional tiebreak to lead the NFC West.

FOOTBALL NEVER STOPS

Live games, analysis and more 7 days a week: Get ESPN+

Buccaneers at 49ers odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 10:14 a.m. ET.

Moneyline (ML): Buccaneers +400 (bet $100 to win $400) | 49ers -550 (bet $550 to win $100)
Against the spread (ATS): Buccaneers +10.5 (-110) | 49ers -10.5 (-110)
Over/Under (O/U): 42 (O: -110 | U: -110)

2023 betting stats

ML: Buccaneers 4-5 | 49ers 6-3
ATS: Buccaneers 6-3 | 49ers 5-4
O/U: Buccaneers 2-7 | 49ers 4-4-1

Buccaneers vs. 49ers head-to-head

This will be the 27th matchup overall and 26th in the regular season for the 2 teams. The 49ers lead 19-6 all-time in the regular season but the Bucs won the one playoff matchup back in 2003.

The 49ers beat the Bucs 35-7 at home last season as QB Brock Purdy had 2 TD passes and a rushing TD.

Bucs QB Baker Mayfield is 0-2 in 2 career appearances against the 49ers. He has not thrown a TD pass against them and has been intercepted 3 times.

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

Facebook Twitter Email