Arizona Cardinals at Houston Texans odds, picks and predictions

Jess Root | Staff Writer

The Arizona Cardinals (2-8) are on the road in Week 11 to take on the Houston Texans (5-4). Kickoff Sunday afternoon from NRG Stadium is at 1 p.m. ET (CBS). Below, we analyze BetMGM Sportsbook's lines around the Cardinals vs. Texans odds, and make our expert NFL picks and predictions.

The Cardinals snapped a 6-game losing streak last week with a 25-23 last-second win over the Atlanta Falcons as 2-point underdogs. It was QB Kyler Murray's 2023 debut, playing for the first time since he tore his ACL last December.

The Texans are coming off 2 straight last-minute wins. Last week, they upset the Bengals in Cincinnati 30-27 on a field goal as time expired as 5.5-point underdogs.

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Cardinals at Texans odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 10:57 p.m. ET.

Moneyline (ML): Cardinals +200 (bet $100 to win $200) | Texans -250 (bet $250 to win $100)
Against the spread (ATS): Cardinals +5.5 (-105) | Texans -5.5 (-115)
Over/Under (O/U): 48 (O: -110 | U: -110)

Cardinals at Texans key injuries

Cardinals

OL Trystan Colon (calf) questionable
RB Emari Demercado (toe) out
OL D.J. Humphries (ankle ) questionable
DL Jonathan Ledbetter (shoulder) out
DL Kevin Strong (knee) questionable
WR Michael Wilson (shoulder) questionable

Texans

DE Will Anderson Jr. (knee) questionable
WR Noah Brown (knee) questionable
RB Dameon Pierce (ankle) out
LB Henry To'oTo'o (concussion) out
S Jimmie Ward (hamstring) out

Cardinals at Texans picks and predictions

Prediction

Texans 28, Cardinals 24

Moneyline

The Cardinals are winless on the road this season while the Texans are 3-1 at home.

Texans QB C.J. Stroud has 6 TD passes in his last 2 games. The Cardinals allow the 2nd-highest passer rating against at 101.0.

The Texans have scored 39 and 30 points in their last 2 games. The Cardinals have allowed 30 or more points 4 times this season.

The Texans should win, but it isn't worth a wager at -250.

PASS.

Against the spread

The Texans needed last-minute drives to win their last 2 games, winning them by a combined 5 points.

Arizona averages over 22 points a game with RB James Conner in the lineup. The Texans have allowed 27 or more points in 2 straight games and struggled in a loss to the lowly Carolina Panthers before that.

This game has the look of a back-and-forth shootout and could come down to the last drive.

BET CARDINALS +5.5 (-105).

Over/Under

The Cardinals' win last week was exactly 48 points. The Texans' last 2 games have had totals of 57 and 76. The Over has hit in 6 of the Cardinals' 10 games this season and in 5 of the 6 games this season when Conner has been in the lineup.

BET OVER 48 (-110).

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