New York Jets at Buffalo Bills odds, picks and predictions

Myles Cohen | Staff Writer

The New York Jets (4-5) head to Orchard Park to face division rival Buffalo Bills (5-5) Sunday for the 2nd time this season. Kickoff is scheduled for 4:25 p.m. ET at Highmark Stadium (CBS) Below, we analyze BetMGM Sportsbook's lines around the Jets vs. Bills odds, and make our expert NFL picks and predictions.

Both teams lost last week. The Jets fell as 1-point road favorites at the Las Vegas Raiders 16-12; the Bills, who were 7.5-point home favorites, dropped a 24-22 decision to the Denver Broncos on Monday Night Football.

Things continue to trend downward for both teams. At least one should win Sunday. The touchdown-resistant Jets continue to have their offense led by QB Zach Wilson, who has only thrown 1 TD in the last 5 games.

Against the Broncos, Bills QB Josh Allen was again inconsistent. He finished with 177 passing yards, 1 TD and 2 picks -- his NFL-leading 10th and 11th interceptions. Following the loss, the Bills fired offensive coordinator Ken Dorsey.

The Jets beat the Bills 22-16 in overtime in the season opener, earning the upset as 2.5-point underdogs. This was the game when New York QB Aaron Rodgers was injured on the Jets' first drive.

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Jets at Bills odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 12:20 a.m. ET.

Moneyline (ML): Jets +275 (bet $100 to win $275) | Bills -350 (bet $350 to win $100)
Against the spread (ATS): Jets +7 (-105) | Bills -7 (-115)
Over/Under (O/U): 39.5 (O: -110 | U: -110)

Jets at Bills key injuries

Jets

CB Michael Carter ll (hamstring) questionable
OL Billy Turner (finger) out
WR Garrett Wilson (elbow) questionable

Bills

LB Matt Milano (leg) out/Injured reserve
DT Jordan Phillips (knee) questionable
WR Trent Sheffield (ankle) questionable

Jets at Bills picks and predictions

Prediction

Bills 24, Jets 13

Moneyline

STAY AWAY.

Although the Bills (-350) will handle the Jets, betting 3.5 times the potential return is not wise.

Against the spread

TAKE BILLS -7 (-115).

The Jets defense has proven to cause issues for Allen, but the Jets offense hasn't scored a touchdown in their last 11 quarters.

This Jets squad certainly has a stellar defense. However, we can never discount Buffalo's home-field advantage. The Bills are 4-1 at home this season and 3-0 at home in the last 3 vs. the Jets.

Expect the Bills to firmly get back on track Sunday.

Over/Under

LEAN UNDER 39.5 (-110).

Both offenses are inconsistent and especially turnover prone. The last 4 head-to-head meetings cashed Under tickets.

The Under is 3-6 in Jets' games this season and 3-7 in Bills' games.

The Jets average 16.0 points per game, ranking 30th, while the Bills defense ranks 5th in points allowed (18.4 PPG).

While the Bills score 26.2 PPG (ranking 8th), the Jets defense yields just 19.1 PPG (ranking 7th).

UNDER 39.5 (-110) is the lean here.

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