Real Madrid vs. Napoli odds, picks and predictions

Real Madrid (4 wins, 0 draws, 0 losses) welcome Napoli (2-1-1) to Santiago Bernabéu Wednesday. Kickoff is set for 3 p.m. ET. Below, we analyze BetMGM Sportsbook's lines around the Real Madrid vs. Napoli odds, and make our best Champions League bets, picks and predictions.

Real Madrid are the only team in Group C having yet to lose a group stage match. They sit with an 11-2-1 record in La Liga play and atop the table in league action. They are led by a star-studded defense, which is allowing just 0.64 goals per game. They have scored 9 goals and allowed 3 through 3 UEFA Champions League games. Offensively, they are led by F Jude Bellingham, who has 11 goals in 12 La Liga matches.

Napoli sit 2nd in Group C and have a 7-3-3 record in Serie A. They sit 4th in the top Italian league. They are averaging 2 goals per game while allowing 1.08. Napoli are led in scoring by F Victor Osimhen, who has 6 goals in 9 matches. Napoli are 2-0-0 in road Champions League matches yet 0-1-1 in home Group Stage competitions.

Real Madrid vs. Napoli odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Tuesday at 11:46 p.m. ET.

• Moneyline: Real Madrid -120 (bet $120 to win $100) | Napoli +300 (bet $100 to win $300) | Draw +280
• Over/Under: 2.5 (O: -160 | U: +115)

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Real Madrid vs. Napoli picks and predictions

Prediction

Real Madrid 2, Napoli 0

Moneyline (ML)

BET REAL MADRID (-120).

Real Madrid have looked unstoppable throughout this season, and they have arguably the best midfielder in the world in Bellingham. They are averaging 2.21 goals per game in league play and are 5-1-0 at home. They are 2-0-0 at home in Champions League play and have outscored opponents by an average of 2 goals per game.

Napoli are a quality opponent, but they don't have the resume and lost to Real 3-2 at home Oct. 3. Expect them to struggle against 1 of the most complete teams in the world. Take REAL MADRID (-120).

Over/Under (O/U)

LEAN UNDER 2.5 (+115).

Both teams have strong defenses. Napoli are allowing 1.08 goals per game in league play, while Real are allowing just 0.64. On top of that, 2 straight Champions League games for Napoli have gone under this total. Both teams in the Oct. 3 meeting went under 2.0 expected goals.

With Real having given up only 3 goals in 3 games throughout this group stage, they should be able to limit Napoli better than they did the 1st time. For this value, bet UNDER 2.5 (+115).

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