First look: Arizona Cardinals at Chicago Bears odds and lines

Jess Root | Staff Writer

The Arizona Cardinals (3-11) are on the road in Week 16 to face the Chicago Bears (5-9). Kickoff at Solider Field is Sunday at 4:25 p.m. ET (FOX). Below, we look at Cardinals vs. Bears odds from BetMGM Sportsbook. Also see: SportsbookWire's NFL picks and predictions.

The Cardinals, coming off their bye, lost to the San Francisco 49ers 45-29 at home on Sunday, failing to cover the 12-point spread as underdogs. They are 2-3 since the return of QB Kyler Murray from injured reserve.

The Bears blew a 17-7 lead on Sunday and lost 20-17 to the Cleveland Browns, failing to cover the 2.5-point spread as road underdogs. The loss snapped Chicago's 2-game winning streak.

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Cardinals at Bears odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 11:03 a.m. ET.

Moneyline (ML): Cardinals +165 (bet $100 to win $165) | Bears -200 (bet $200 to win $100)
Against the spread (ATS): Cardinals +4.5 (-110) | Bears -4.5 (-110)
Over/Under (O/U): 44.5 (O: -110 | U: -110)

2023 betting stats

ML: Cardinals 3-11 | Bears 5-9
ATS: Cardinals 7-6-1 | Bears 6-6-2
O/U: Cardinals 8-6 | Bears 7-7

Cardinals vs. Bears head-to-head

The Cardinals and Bears have a rivalry that dates back to 1920 when both teams were in Chicago. They have played each other 92 times. The Bears lead the all-time series 57-29-6.

The road team has won the last 6 matchups The Cardinals have won 3 straight meetings in Chicago, including their last meeting in 2021, a 33-22 Cardinals win.

Cardinals QB Kyler Murray played in that 2021 win, his only career start against the Bears, throwing 2 TD passes and rushing for 2 scores as well.

Bears QB Justin Fields has not faced the Cardinals. He was injured when the 2 teams last played.

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