First look: New England Patriots at Buffalo Bills odds and lines

Nathan Beighle | Staff Writer

The Buffalo Bills (9-6) welcome the New England Patriots (4-11) to Highmark Stadium Sunday. Kickoff is set for 1 p.m. ET (CBS). Below, we look at Patriots vs. Bills odds from FanDuel Sportsbook. Also see: SportsbookWire's NFL picks and predictions.

The Bills beat the Los Angeles Chargers 24-22 Saturday, but failed to cover as 13-point road favorites. Buffalo has won 3 straight games and covered in 2 of them. However, it is just 3-7-1 against the spread (ATS) over its last 11 and 4-3 ATS at home. The Bills are led by QB Josh Allen, who has 3,778 passing yards and 40 total TDs.

The Patriots beat the Denver Broncos 26-23 Sunday in Week 16 action, covering as 7-point road underdogs. New England is just 5-10 ATS on the season but has won 2 of its last 3 and covered in all 3. It is 3-4 ATS on the road. The Patriots are now led by QB Bailey Zappe, who has 975 passing yards and 6 TD in 4 starts (8 games played).

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Patriots at Bills odds

Provided by FanDuel Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Monday at 9:12 a.m. ET.

Moneyline (ML): Patriots +500 (bet $100 to win $500) | Bills -700 (bet $700 to win $100)
Against the spread (ATS): Patriots +11.5 (-115) | Bills -11.5 (-105)
Over/Under (O/U): 40.5 (O: -110 | U: -110)

2023 betting stats

ML: Patriots 4-11 | Bills 9-6
ATS: Patriots 5-10 | Bills 6-8-1
O/U: Patriots 6-9 | Bills 5-10

Patriots vs. Bills head-to-head

For a long time the AFC East rivalry was owned by the Tom Brady-led Pats which has led to New England having a 78-49-1 record in the series.

However, Buffalo snapped a 7-game losing skid in 2020, and it has won 6 of the last 8 between the teams. The Patriots did win earlier this season, taking down Buffalo at home 29-25 in Week 7.

QB Mac Jones, who isn't expected to start, had a near-perfect game, throwing for 272 yards and 2 TDs. Despite the lopsided records, both teams are 2-2 in divisional play this season.

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