Kansas City Chiefs at Los Angeles Chargers odds, picks and predictions

Drew Phelps | Staff Writer

The Kansas City Chiefs (10-6) and Los Angeles Chargers (5-11) meet at SoFi Stadium Sunday. Kickoff is set for 4:25 p.m. ET (CBS). Below, we analyze FanDuel Sportsbook's lines around the Chiefs vs. Chargers odds, and make our expert NFL picks and predictions.

Kansas City picked up a 25-17 win over the Cincinnati Bengals Sunday to clinch the AFC West while covering as a 7-point favorite. QB Patrick Mahomes completed 21 of 29 passes for 245 yards and 1 TD while RB Isaiah Pacheco racked up 130 rushing yards on 18 carries and 1 receiving TD. The Chiefs have scored over 30 points just 1 time in their last 9 games.

Los Angeles has now dropped 4 consecutive games after a 16-9 loss to the Denver Broncos Sunday while failing to cover as a 3.5-point road underdog. RB Austin Ekeler has not produced 70 yards or more rushing since Week 1. Los Angeles has allowed 24 or more points in 3 of its last 4 games and has been held to single digits in 2 of its last 4.

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Chiefs at Chargers odds

Provided by FanDuel Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 6:15 p.m. ET.

Moneyline (ML): Chiefs +152 (bet $100 to win $152) | Chargers -180 (bet $180 to win $100)
Against the spread (ATS): Chiefs +3.5 (-110) | Chargers -3.5 (-110)
Over/Under (O/U): 35.5 (O: -106 | U: -114)

Chiefs at Chargers key injuries

Chiefs

LB Nick Bolton (wrist/abdomen) questionable
DE Michael Danna (not injury related) questionable
DE George Karlaftis (not injury related) questionable
QB Patrick Mahomes (rest) out
CB Trent McDuffie (shoulder) questionable
RB Isiah Pacheco (quad/shoulder) questionable
WR Rashee Rice (hamstring) out
OT Donovan Smith (neck) out
CB L'Jarius Sneed (calf) out
WR Kadarius Toney (hip/ankle) out

Chargers

WR Keenan Allen (heel) out
OLB Joey Bosa (foot) out
LB Justin Hollins (shoulder) out
OG Zion Johnson (neck) doubtful
CB Deane Leonard (heel) questionable
LB Kenneth Murray Jr. (shoulder) doubtful
TE Stone Smartt (shoulder) questionable
LB Tuli Tuipulotu (ankle) questionable
DL Nick Williams (shoulder) out

Chiefs at Chargers picks and predictions

Prediction

Chargers 14, Chiefs 10

Moneyline

PASS.

I recommend you staying away from this game when it comes to the moneyline and spread. The Chiefs are locked into the 3rd seed in the AFC, and nothing that happens in this game will change that fact. Because of that, Kansas City will be resting most of their key starters in preparation of the playoffs.

The Chargers (-180) are playing out the string with a backup quarterback and an interim coach. I truly don't know what you are going to get out of this offense.

Against the spread

PASS.

Just like I mentioned above, there is no reason to bet on the moneyline or spread in this game. It's almost a glorified preseason game with so many backups playing.

Over/Under

BET UNDER 35.5 (-114).

You'll have a bunch of 2nd stringers playing across both lineups; I doubt very many points will be produced.

The Chiefs have had problems scoring with all of their starters playing, and I don't think the back-ups will have much luck, either. The Under has hit in 3 of the last 4 Chiefs games. The Chargers have scored single-digit points in 3 of their last 5 games.

This game is destined to go Under.

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