Seattle Seahawks at Arizona Cardinals odds, picks and predictions

Jess Root | Staff Writer

The Seattle Seahawks (8-8) and Arizona Cardinals (4-12) wrap up their regular seasons Sunday. Kickoff from State Farm Stadium is set for 4:25 p.m. ET (FOX). Below, we analyze BetMGM Sportsbook's lines around the Seahawks vs. Cardinals odds, and make our expert NFL picks and predictions.

The Seahawks were 4.5-point home favorites last week against the Pittsburgh Steelers but lost 30-23 as they allowed over 200 rushing yards. They have lost 5 of their last 7 games.

The Cardinals are coming off a 35-31 road win over the Philadelphia Eagles last week when they were 12.5-point underdogs. They are 3-4 since QB Kyler Murray returned to the lineup.

FOOTBALL NEVER STOPS

Live games, analysis and more 7 days a week: Get ESPN+

Seahawks at Cardinals odds

Provided by BetMGM Sportsbook; access Paste BN Sports Scores and Sports Betting Odds hub for a full list. Lines last updated Saturday at 5:30 p.m. ET.

Moneyline (ML): Seahawks -150 (bet $150 to win $100) | Cardinals +125 (bet $100 to win $125)
Against the spread (ATS): Seahawks -3 (-105) | Cardinals +3 (-115)
Over/Under (O/U): 47.5 (O: -110 | U: -110)

Seahawks at Cardinals key injuries

Seahawks

LB Nick Bellore (knee) questionable
LB Jordyn Brooks (ankle) available
DE Mario Edwards (knee) out
OL Abraham Lucas (knee) out
NT Jarran Reed (knee) questionable

Cardinals

DL Leki Fotu (hand) questionable
LB Dennis Gardeck (knee) questionable
OL Elijah Wilkinson (illness) questionable
CB Garrett Williams (ankle) out

Seahawks at Cardinals picks and predictions

Prediction

Seahawks 27, Cardinals 24

Moneyline

The Cardinals have only 2 home wins all season. The SEAHAWKS (-150) need this game. They must win and need Green Bay to lose to Chicago to make the playoffs. And after being physically dominated by the Steelers, they will be locked in.

However, the Seahawks' run defense, which was 1 of the league's best when these teams played in Week 7, has gotten worse over the course of the season. Seattle allows 4.5 yards per carry and 134.1 yards per game on the ground.

The Cardinals have rushed for 200 yards as a team in 2 of their last 3 games.

But while the Cardinals dominated in their win over the Eagles, possessing the ball almost 40 minutes, the Philly offense scored 24 points in just over 20 minutes of possession.

They have allowed NFC West running backs to gain an average of more than 160 scrimmage yards and 2 touchdowns per game.

Seattle needs this game more than the Cardinals.

BET SEAHAWKS (-150).

Against the spread

The 3-point spread is tough.

Arizona should be able to move the ball against Seattle's defense, but expecting it to have the ball for 40 minutes is unreasonable. Arizona's defense doesn't stop anyone. It has allowed 31, 27, 45 and 37 points in 4 of their last 5 games.

This game will likely come down to the final minute.

I expect Seattle to win it late, but in terms of a spread bet, I can totally see this being a 3-point game.

Rather than the -3 (-105), BET SEAHAWKS ALTERNATE SPREAD -2.5 (-125) to avoid the push.

Over/Under

Five of the Cardinals' last 10 games have had totals in the 50s.

The Seahawks' last game had 53 total points.

These are teams with bad defenses.

BET OVER 47.5 (-110), and I really like for a little better payout, OVER ALTERNATE TOTAL 50 (+110). That would make a nice little ladder.

Play our free daily Pick’em Challenge and win! Play now!

For more sports betting picks and tips, check out SportsbookWire.com and BetFTW.

Follow Jess Root on Twitter/X. Follow SportsbookWire on Twitter/X and like us on Facebook.

Access more NFL coverage:

[]

Facebook Twitter Email